Vascular Calcification Therapeutics Lab

Vascular Calcification Therapeutics Lab team photo

Overview

Our lab is dedicated to advancing the understanding and treatment of vascular calcification through innovative, curiosity-driven research and an inclusive scientific environment. We investigate the activation, progression, and potential reversal of arterial calcification, with particular focus on therapeutic strategies involving cell and gene therapy. By uncovering these mechanisms, we aim to develop new approaches that transform how vascular calcification is prevented, treated, and potentially reversed.

Beyond discovery, our work is grounded in a commitment to addressing inequities in cardiovascular health. We focus on individuals affected by vascular calcification and communities facing structural barriers to healthy living. Through scientific research and community education, we strive to improve cardiovascular outcomes and promote disease prevention.

Ultimately, we envision a future where vascular calcification is not only better understood but also treatable and preventable. We are committed to translating these discoveries into improved cardiovascular health by addressing health disparities, supporting communities affected by vascular calcification, and promoting education on low-phosphate dietary practices.

Mission

Our lab seeks to advance scientific understanding of vascular calcification by investigating its activation, progression, and potential reversal. By combining rigorous science with inclusive collaboration and community engagement, our lab seeks to reshape clinical care, challenge health disparities, and help redefine who participates in and leads scientific discovery.

Team

Headshot of LaShan Hendrix

LaShan Hendrix

Assoc Professor, CEAS - Biomedical Eng

201 UCBIOSCI

513-556-7716

Dr. C. LaShan Simpson Hendrix is an Associate Professor in the Department of Biomedical Engineering at the University of Cincinnati. Before joining the faculty at University of Cincinnati in 2024, she was an Associate Professor at Mississippi State University (2013 – 2023) and she trained as a postdoctoral research associate at Rice University in the Department of Bioengineering. Dr. Hendrix received all her educational training at Clemson University with a B.S. in Biochemistry, M.S., and Ph.D. in Bioengineering. Dr. Hendrix’s research interests include vascular calcification, smooth muscle cells, cell and gene therapy, and mechanotransduction. Her work has been funded by the National Science Foundation (NSF), the National Institutes of Health (NIH), and the United States Department of Agriculture (USDA).
 
In addition to her passion for vascular research, Dr. Hendrix is a student advocate and a champion for diversity and inclusion. She has worked to create inclusive spaces for trainee development and success. She has received numerous awards for her efforts including Teacher of the Year, College of Agriculture and Life Sciences at Mississippi State University, 2018; Academy of Distinguished Teachers, Bagley College of Engineering at Mississippi State University, 2019; and Excellence in Diversity and Inclusion Award, Mississippi Institute of Higher Learning, 2020.

Her pride and joy are the diversity of her research lab and the outstanding accomplishments of her trainees. Dr. Hendrix is the founder of BlackWomenInBME and has hosted sessions for her group at the Biomedical Engineering Society (BMES) Annual meeting since 2018. She is the recipient of the 2021 Biomedical Engineering Society Diversity Award Lecture.